PHGY 214 Study Guide - Final Guide: Laron Syndrome, Menstruation, Glycogenesis
11 Apr 2018
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Organs affect by 1+ hormones: adrenal cortex: aldosterone, progesterone, cortisol, androgens, ovary: androgens, estrogen, progesterone, placentra: hcg, estrogen, progesterone, placentral lactogen, anterior pit: prolactin, tsh, lh, fsh, gh, acth. Hormones w 1+ target cells: testosterone: spermatogenesis (lh increased testo+ fsh androgen binding protein, oxytocin: stim uterine and mammary myoepithelial contraction. Adipose: primary storage site, free fatty acids for postab state. Brain: can only use glucose, cannot use glycogen. Hepatocytes: glut2 not insulin dependent, glucose moves into liver signal cascade increases hexokinases 6 p glucose so [] of glucose stays low and can continue to move into liver. Adipose + muscle: glut4 is insulin dependent and takes up glucose in adipose and skeletal muscle when insulin binds. Fasted state: glucose leaves cell, low hexokinase and insulin: brain + b cells in intestines are not affected. Growth: det by gh but influenced by, genetics, stress, diet, disease, gonadal steroids, with age= less gh but minimal impact bc growing is done.
