ANAT 261 Lecture Notes - Lecture 4: Dense Irregular Connective Tissue, Loose Connective Tissue, Stratum Granulosum

• School: McGill University
• Department: Anatomy & Cell Biology
• Course: ANAT 261
• Professor: Craig A.Mandato

Document Summary

Connective tissue: why does a tan fade but tattoo stay, tattoos damage, epidermis, epidermal-dermal junction (the basement membrane, upper layer of the dermis (papillary layer) Initially, the ink is dispersed in the upper dermis. The damaged layers will end up homogenized (mushy) In 7-13 days: the ink will aggregate (mostly still in the dermis, the ink gradually is taken up by keratinocytes (epithelial cell) and phagocytotic cells (including fibroblast and macrophages/wbc) In 1 month: the basement membrane is reforming (basal cells, in stratum granulosum, contain ink) In the dermis, ink-containing phagocytotic cells are concentrated along the bm, below a layer of granulation tissue (blood vessel rich, pre-curser to scars) that is surrounded by collagen. Ink still being eliminated through epidermis (because the cells will slough off) with ink that will stay in keratinocytes, macrophages and fibroblasts. In 2-3 months: bm is fully reformed (prevents further loss of ink through the epidermis)