MICI 2100 Lecture Notes - Lecture 12: Viral Tegument, Virus, Golgi Apparatus
1 Oct 2016
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Physical properties of viruses: capsids (protein shells, genomes (dsdna, ssdna, dsrna, +ssrna, -ssrna, optional components: o tegument o envelope. Virus particle: molecular structures that package virus genomes in infected cells and transmit them to new host cells. It must be: correctly assembled, escape the cell in which they are made, withstand the extracellular environment, attach and enter another host cell, release viral genome. These rules explain why there is so much diversity in viruses; each virus has different challenges in its host cells and extracellular environments. These are called capsomers: damage to one or more subunits may render that particular subunit non-functional but does not destroy the infectivity of the whole particle. Rna). o length and diameter of helix depend on length of genome and the added length of a capsomers and the width of the. Rna helix. o freankel-conrat and williams showed that a mixture of purified tmv rna and coat were incubated together virus particles formed spontaneously.
