ANHB1101 Lecture Notes - Lecture 34: Molecular Sieve, Ground Substance, Loose Connective Tissue
5 Sep 2018
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Cells are widely spaced compared to other tissues (separated by extracellular matrix - produced by cells). Matrix determines the properties of the ct type. Matrix made up of bres and ground substance. (fibres = proteins manufactured by cells). Functions; binding and packing (epithelium, around organs, joints, fat), support (bone, cartilage, fat), protection (bone), insulation (fat), transport (blood - immunity etc. Comes from mesoderm of the 3 germ layers. Mature cells can revert to immature forms to repair the tissue to undergo mitosis. ground substance; clear, amorphous, viscous uid/gel. Functions; ll space, acts as molecular sieve, allows for rapid diffusion of small molecules, barrier to large molecules+foreign particles eg. bacteria, transport of metabolites to and from blood vessels to epithelium (epithelium is avascular), maintains homeostasis, composed of interstitial. Uid+cell adhesion proteins to loosely anchor the cells in place+hydrophilic molecules to trap and hold water in place. General/ brous loose - reticular + areolar areolar - all 3 bre types.
