ANHB1101 Lecture Notes - Lecture 20: Open Reading Frame, Dna Replication, Nuclear Membrane

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Bottom layers differentiate (from stem cells) and move up and then move off and die and are replaced. Nucleosome groups of dna wrapped around histones. G1 phase moves to s phase is when mutations most often occur creates cancer cells. G2 phase final prep and check before cell division. Anaphase chromosomes split at centromere and pulled to opp poles (centrioles on each side). Dna makes rna (transcription) which codes for amino acids which form proteins in ribosomes. Transcription dna transcribed to mrna (inside nucleus) mrna leaves nucleus (hits rough er) and directs protein assembly on ribosomes (translation). Protein leaves ribosome in vesicle - moves to golgi and is packaged etc. U is more energy efficient to the cell. T instead of u in dna bc most common mutation in dna would be a to u. Open reading frame between start and end codons.

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