HUMB1000 Lecture Notes - Lecture 13: Microtubule, Sister Chromatids, G2 Phase

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After uniting in the centre, they are a double stranded chromosome. Mitosis is the division of the nucleus, cytokinesis is the division of the rest of the cell. Somatic cell: forms the body of a multicellular organism. Before cell division, the centrioles divide, move to the ends of the cell and organise spindle fibres. 2 identical sets of chromosomes moved to separate ends of the cell. Nuclear envelope reforms around each set of chromosomes. Resulting m+f gametes unite to form a zygote. Sister chromatid strands of each chromosome no longer identical. Results in exchange of genetic material between maternal and paternal chromosomes, and so new gene combinations. Prophase 1: chromosomes become visible and spindle fibres begin to form. Metaphase 1: homologous chromosomes line across equator randomly and spindle fibres attach to the centromeres. Unlike mitosis, there are two spindle fibres to each chromosome (pulls chromosome apart at the centromere) Anaphase 1: chromosomes pulled apart from one another by spindle fibres.

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