CHEM 2444 Chapter Notes - Chapter 13: Protic Solvent, Sn1 Reaction, Sodium Amide
Document Summary
Alkenes & alkynes: react as br nsted-lowry bases with hx or catalytic h+ and water or roh via carbocation intermediates, react with the most readily available nucleophile, pi bonds of alkenes/alkynes react as lewis bases with. Alkyl halides: react with nucleophiles by sn2 or sn1 to give substitution products. Etc: a nucleophile donates two electrons to carbon, polarizing the carbon of the alkyl halide. Nucleophile attacks carbon, replaces bromine (sn2: when the alkyl halide ionizes to a carbocation & reacts subsequently with a nucleophile. this is an sn1 reaction. Ionization is very slow in anything except water: react with strong bases via e2 or e1 to give alkenes. Can remove beta hydrogen, forming an alkene, kicking out leaving group (e2) In water, can ionize into a cation, then the base removes the proton (e1) Bases: reaction 1 step-by-step (basic bronsted-lowry acid-base reaction)
