NURS 165 Study Guide - Final Guide: Tachycardia, Ketoconazole, Nonsteroidal Anti-Inflammatory Drug
Acute Coronary Syndrome, Atherosclerosis, Thromboembolism MEDS
Add notes from last week!!
• Prototypes
o Nitroglycerin
▪ Indication is for angina (that chest pain)
▪ Vasodilates via NO
▪ Doesn’t work by an enzyme or receptor like most drugs!!
• Generates metabolic substrate
▪ Dose depends on form of drug
• Form depends on what you’re using drug for
• Stable angina – small dose
• Larger doses
▪ Check onset, etc.
o Metroprolol
▪ Indications
• Hypertension
• Angina
• HF
• MI
▪ Beta 1 blocker
• Blocks adrenergic receptor
• Can also block beta 2 and 3
o If pt. gets too much of drug, selectivity can be
overcome
o Aspirin
▪ Indications
• Primary and secondary prevention of CVD
• Pain and inflammation
▪ Mechanism of action
• Same as all other uses!
• PLATELET AGGREGATION, inhibiting COX
o Irreversible effect for full platelet life (7-10 days)
o Others that ) wasn’t paying attention for check slides
o Heparin
▪ Units represent activity of drug
o Enoxaparin
▪ Treats/prevents thrombosis
▪ Increases antithrombin activity
• Inactivates Xa get it that’s why there’s Xa in the drug
o Dabigatran
▪ Prevention of systemic embolism/stroke in Afib patients
▪ Competitive thrombin inhibitor
o Rivaroxaban
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