BIO SCI 93 Study Guide - Midterm Guide: Aminoacyl-Trna, Dna Polymerase Iii Holoenzyme, Start Codon

• School: UC-Irvine
• Department: Biological Sciences
• Course: BIO SCI 93
• Professor: Jorge Busciglio Kim Green Marcelo A Wood

Document Summary

Purines (long structure): a, g; pyramidines (short structure): c, t. Dna is synthesized in the direction of 5" to 3". Two dna strands are separated, opening up a replication bubble. Replication forks: where dna strands are unwounded. Helicase: enzymes that untwist the double helix at the replication forks; starts separate the dna in the regions with high a-t (2 hydrogenate bonds). Topoisomerase: corrects overwinding ahead of replication forks. Single strand binding protein: binds to and stabilizes single- stranded dna until it can be used as a template. Dna polymerase: elongate of new dna at a replication fork. + dna pol i: replace rna with dna. + dna pol iii: using parental dna as a template, synthesizes new dna strand by adding nucleotides to an rna primer or pre-existing dna strand. Okazaki fragment: a series of segments in which the lagging strand is synthesized.