HE201 Final: Nuero -second file
Document Summary
Slow responses in which the nt receptor is coupled to a g-protein. In both slow responses, binding of nt to receptor activates a g protein. Change in membrane potential in response to receptor-nt binding: occurs very quickly and terminates rapidly because the channel closes as soon as the nt leaves the receptor. Once that brings the membrane potential of the post-s neuron closer to the threshold for generating an action potential: excitatory synapses depolarize the post-synaptic neuron. Excitatory postsynaptic potential (epsp: can occur as either a fast response or a slow response. The membrane potential will not return to resting conditions until the k channels are dephosphorylated; will not occur until enough camp has be degraded. In comparison to fast epsps, slow epsps take longer to develop and last longer (seconds to hours) Takes the membrane potential of the post-s neuron away from the action potential threshold by hyperpolarizing the neuron: alternatively, stabilizing the membrane potential at the resting value.
