BIO380H5 : BIO 380 Exam Notes!!!!!!!!!!!
Document Summary
Lecture 1: introduction to developmental biology: human development divided into prenatal (before birth) and post-natal periods, human development starts with: Developmental biology model organisms: fruit fly: most understood animal in development, zebrafish: transparent, mouse: mammal, closest model organism to us, frog: huge eggs, can exploit genome. 3 distinct germ layers: fertilized egg undergoes divisions to form 3 germ layers. What is a stem cell: stem cell can make more stem cells while also producing cells committed to undergoing differentiation, retains ability to divide and replicate itself, but can also specialize into a differentiated cell type. Maturational series of stem cells: totipotent: can form any cell type (zygote) pluripotent: can produce all embryonic cells multipotent: make cells of where they reside limited differentiation potential. Limited division potential functional cell (no longer stem cell, just a regular functional cell) In vitro (test tube) repair tissues or model disease/development.
