NURS 2550H Study Guide - Final Guide: G Protein–Coupled Receptor, Intrinsic Factor, Intrinsic Activity

• School: Trent University
• Department: Nursing
• Course: NURS 2550H
• Professor: Ellen Buck- Mc Fadyen

Document Summary

Dose-response relationship: relationship between the size of an administered dose and the intensity of the response produced. Finds: maximum response a drug can cause, how much of an increase in the dose is needed for desired effect the minimum amount of a drug we can use. Graded vs. all-or-nothing principle: graded: as the dosage increases, the response becomes progressively larger, all-or-nothing: drug produces only one intensity, cannot adjust. Maximum efficacy: the largest effect a drug can produce: whichever has the highest maximum point, we would say has a greater maximum efficacy. Potency: the amount of drug we must give to elicit an effect: potent drug is the one that produces its effects at low doses, potency and maximum efficacy not related. Receptor: any functional macromolecule in a cell to which a drug binds to produce its effects: body"s own receptors for hormones, neurotransmitters, and other regulatory molecules, enzymes and ribosome can be thought of target molecules.