HLSC 2P09 Study Guide - Midterm Guide: Beta Cell, Skeletal Muscle, Saxitoxin

• School: Brock University
• Department: Health Sciences
• Course: HLSC 2P09
• Professor: Evangelia Tsiani

Document Summary

Excitable cells capable of self-generation of electrochemical impulses at their membranes. Nernst potential the potential across the membrane that prevents net diffusion of an ion in either direction through the membrane. Goldman hodgkin katz is used to calculate rmp: contribution of all ions that cross the membrane. Depolarization is moving the potential towards zero, it is possible to overshoot and end up with a + ve potential. Repolarization is process of getting back to normal -70mv. Hyperpolarize is when it goes a bit more negative than the resting potential -90mv. Beta cell depolarization & insulin release: low glucose levels in blood, metabolism slows, atp decreases, katp channels open, cell at resting membrane potential; no insulin is released. Secreting insulin: high glucose levels in blood, metabolism increases, atp increases, katp channels closes. Means by which nerve signals are transmitted. Resting stage (membrane polarized, negative potential), depolarizing stage( membrane permeable to na+, influx of na+, membrane depolarization) repolarizing stage (permeable to.