PSY2071 Study Guide - Final Guide: Nucleus Accumbens, Hyperfunction, Prefrontal Cortex

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The more the person uses substances, the more he/she loses control of his/her behavior due to changes in brain development. Mesolimbic da: full of d2 receptors (one of the four dopamine systems) sensitivity to rewards. Hypersensitive to rewards (hyperfunction of that nucleus accumbens) --> more willing to engage in reward bases activities. Dorsal stratum: a behavior that is treated with a rewarding system forms a habit. Prefrontal cortex systems: behaviors habituated, system that normally avoids/controls that behavior becomes weaker --> behavior becomes more out of control. Genes --> brain circuits --> personality traits --> mental health disorder (substance use disorder) Addiction has the factor of genetic vulnerability in such a way that the genetic vulnerability affects how the brain develops and in turn the personality traits. Negative affective system will affect the negative affects (more nerotic) --> more vulnerable to addiction. D4, dat: dopamine d4 receptors (4 different system; this is the cortical.

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