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A polyribosome is

a. a complex of many ribosomes and an mRNA.

b. a complex of many ribosomes in eukaryotes.

c. an initiation complex in eukaryotes.

d. an elongation complex in eukaryotes.

e. a complex of a ribosome with its two subunits and several mRNAs.

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Related questions

1. The extended polypeptide chain occurs in the E site in the ribosome

True

False

2. In Prokaryotic translation which of the following occurs:

a) the 50S ribosome joins with the 60S initiation complex to allow for initiation

b) The AUG is identified by being 20 nucleotides downstream of the shine-dalgarno sequence

c) GTP is hydrolyzed as initiation factors are released

d) A 45S initiation complex is formed by numerous factors, including mRNA

Eukaryotic transcription normally takes place on a chromatin template at nuclease-accessible sites.(True/False)

*After promoter clearance by RNA polymerase II:

A) all associated factors remain bound to the polymerase for elongation.

B) a subset of factors remain at the promoter region.

*Which of the following statements is FALSE?

A) RNA polymerase II is responsible for the transcription of genes encoding protein-coding sequences only.

B) Many promoters recognized by RNA polymerase II contain regulatory elements several kbp upstream of the initiation site.

C) TFIIB has a role in converting a closed-promoter into an open-promoter complex.

D) The C-terminal domain of the largest subunit of RNA pol II undergoes extensive phosphorylation prior to transcription elongation.

E) A multiprotein complex is involved in communication between upstream control elements and proteins bound at the promoter.

C) no further elongation factors are acquired by the polymerase.

D) no further chromatin remodeling is required.

E) transcription continues until the polymerase reaches the poly (A) tail

*In eukaryotes RNA polymerase I transcribes all of the ribosomal RNA components.(TRUE/FALSE)

3. Compare and contrast transcription termination in bacteria and eukaryotes.

a) What sites signal the transcription complex to terminate in prokaryotes and to terminate/polyadenylate in eukaryotes?

b) What proteins, if any, bind to these sites and what do they do?

c) What determines the 3รขย€ย™ end of the message?

d) When does Pol II really terminate transcription?

e) Compare and contrast rRNA processing and splicing?

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