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5 Feb 2018
A population in Chile that lives in a harsh desert environment had an outbreak of cholera during the summer that killed many people. This population was tested for the presence of CFTR alleles. The numbers of each genotype are shown below.
+ / + + / â F508 âF508 / âF508 Total
Spring 1489 570 91 2150
Fall 780 570 0 1350
a. What is the fitness of each genotype?
b. What are the allele frequencies in the Fall population?
c. Assuming no further disease outbreaks occur, what will be the allele frequencies in the next generation?
d. What will be the genotype frequencies in this next generation?
e. Provide a biochemical, cellular, or molecular hypothesis as to why the three different genotypes should have different fitness.
A population in Chile that lives in a harsh desert environment had an outbreak of cholera during the summer that killed many people. This population was tested for the presence of CFTR alleles. The numbers of each genotype are shown below.
+ / + + / â F508 âF508 / âF508 Total
Spring 1489 570 91 2150
Fall 780 570 0 1350
a. What is the fitness of each genotype?
b. What are the allele frequencies in the Fall population?
c. Assuming no further disease outbreaks occur, what will be the allele frequencies in the next generation?
d. What will be the genotype frequencies in this next generation?
e. Provide a biochemical, cellular, or molecular hypothesis as to why the three different genotypes should have different fitness.
Lelia LubowitzLv2
7 Feb 2018
