Log in
Biology
3
answers
0
watching
146
views
22 May 2018

An individual is deficient in the complement component C3. Describe the consequences of this deficiency for each of the following:

What is the specific role of C3 in the following processes:

1. activation of the membrane-attack complex (MAC)

2. phagocytosis of pathogens

3. clearance of immune complexes

4. presentation of antigenic peptides from infectious bacteria

Watch
3
answers
0
watching
146
views

For unlimited access to Homework Help, a Homework+ subscription is required.

Unlock all answers

Get 1 free homework help answer.
Already have an account? Log in
Share
Already have an account? Log in
Share
Sixta Kovacek
Sixta KovacekLv2
23 May 2018
Already have an account? Log in
Share

Related textbook solutions

Molecular Cell Biology
8 Edition,
Lodish
ISBN: 9781464183393
Biology: Science for Life with Physiology
6 Edition,
Belk
ISBN: 9780134555430
Concepts of Biology
OER Edition,
Openstax
ISBN: 9781938168116
Biology
2nd Edition, 2013
Openstax
ISBN: 9781947172517
Essentials of Biology
5 Edition,
Mader
ISBN: 9781259660269

Related questions

Case 32: Deficiency of the C8 Complement Component Questions

C) Bacteria of the genus Neisseria are encapsulated in a thick carbohydrate capsule. Clinical evidence shows that the membrane-attack complex is vital in host defense against these bacteria. It is obvious that the hydrophobic components of the membrane-attack complex cannot penetrate the polysaccharides of the bacterial capsule. How, then, is complement involved in bacterial killing?

D) Patients who are completely deficient in C1q, C1r, C1s, or C4 sustain persistent and severe immune-complex disease such as glomerulonephritis, which can ultimately be fatal. In contrast, patients who are C2-deficient usually sustain only minor forms of immune-complex disease. How do you explain this difference?

Which of the following is a characteristic of the adaptive immune system?

a .It is a specific response against microbial antigen

b. It includes inflammation.

c. It activates the alternative complement pathway.

d. It includes defenses on the body surfaces.

2. C-reactive protein is an opsonin because it:

a. creates a channel in bacterial membranes

b. increases C3b binding to a microbe.

c. forms the pathogen-associated molecular patterns.

d. enhances phagocytosis.

3. The rapid increase in antibody production after repeated exposures to the same antigen is due to:

a. antibody-dependent cellular cytotoxicity.

b. higher levels of IgE

c. presence of memory cells.

d. clonal proliferation of NK cells

4. Cytotoxic T cells can kill cancer cells by:

a. inducing apoptosis with granzyme.b. release of membrane attack complex.

c. activate the production of complement C3b

d. phagocytosis of opsonized cells.

5. Which event is not required for the activation of helper T cells?

a. The presence of interleukin-1

b. Binding of CD8 receptors

c. Binding of matching non-antigenic proteins of the antigen-presenting cel

d. Presentation of an antigen bound to class II MHC

1.How do some pathogens prevent complement activation or avoid the effects of activated complement?

A. some pathogens hijack the host's regulatory membrane proteins that inactivate C3b, preventing the triggering of the alternative activation pathway AND some pathogens produce C5a peptidase that causes destruction of phagoctyes recruited to the area of infection

B. some pathogens produce C5a peptidase that causes destruction of phagoctyes recruited to the area of infection

C. some pathogens produce C5a peptidase that destroys complement C5a, a chemoattractant that recruits phagocytes to the area of infection

D. Some pathogen hijack the host's regultory membrane proteins that inactivate C3b, preventing the triggering of the alternative activation pathway AND some pathogens produce C5a peptidase that destroys complement C5a, a chemoattractant that recruits phagocytes to the area of infection.

2. One of the most important jobs of dendritic cells is

A. production of complement proteins

B. activation of T cells by breakdown of whole antigens and presentation of antigenic epitopes on MHC molecules

C. stimulation of cytokine production by neutrophils

D. activation of B cells by combining epitopes and presentation of whole antigens on MHC molecules

E. production of IgD

3. Normal Microbiota

A. play no role in affecting pathogen growth

B. are the organisms that typically reside on and in your body

C. enhance infection by pathogens

D. are the organisms that typically reside on and in your body AND protect aganist infection by pathogens

E. protect against infection by pathogens.

4. why is the process of gene rearrangement used in creating antibodies and T-cell receptors (TCRs) so important?

A. the given choices are all reasons that generearrangement is critical in adaptive immunity

B. This is how our systems produce memory of previous exposures, a key trait in adaptive immune responses

C. without it, we would need a single gene for every antibody and TCR required to mount all the possible responses needed during our lives

D. interactions with antigens stimulate cells to initate these processes, building the best and strongest response possible to that antigen

E. this is the same DNA altering process that leads to cancer. Understanding it leads to better treatments for cancer.

A.

Related Documents

BIO 3124 Lecture Notes - Lecture 4: Monomer, Idiotype, Vasodilation
turquoiseant153
BIO120H1 Chapter Notes - Chapter 9: Active Transport, Immunoglobulin A, Immunoglobulin D
sapphiremuskrat637
BIO120H1 Chapter Notes - Chapter 2: C-Reactive Protein, Factor H, Conformational Change
sapphiremuskrat637

Weekly leaderboard

Home
Homework Help 3,900,000
Biology 460,000
Start filling in the gaps now
Log in