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23 Jun 2018
1. What is the role of primary lymphoid follicles in eliminating B cells that have antigen receptors specific for soluble self antigen?
2. What is "affinity maturation"? Affinity maturation of the B cell response has been likened to a process of "Darwinian selection". Explain how so?
3. If you could produce a strain of mice in which the follicular dendritic cells of the lymphoid organs were deleted, list the differences in the humoral immune response you might expect to see.
1. What is the role of primary lymphoid follicles in eliminating B cells that have antigen receptors specific for soluble self antigen?
2. What is "affinity maturation"? Affinity maturation of the B cell response has been likened to a process of "Darwinian selection". Explain how so?
3. If you could produce a strain of mice in which the follicular dendritic cells of the lymphoid organs were deleted, list the differences in the humoral immune response you might expect to see.
Sixta KovacekLv2
24 Jun 2018