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In some experimental systems, a newly synthesized RNA primer is transferred from primase to the clamp or clamp loader rather than directly to DNA polymerase. Explain why this would maximize the efficiency of DNA replication.

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Jean Keeling
Jean KeelingLv2
29 Sep 2019

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Related questions

During DNA replication, RNA primase puts an RNA primer in thelagging strand. What is the function of this RNA primer? Why can'tthe enzymes put DNA fragments directly?

Which of the following is correct about DNA replication? A. Replication begins from one end of the molecule, and ends at the other end. B. A type of RNA polymerase is the enzyme that lays down the first nucleotide of the daughter strand. C. Replication occurs in one chromosome at a time. D. DNA polymerase III and the primase have opposite directions of functions. E. At the end of replication, two DNA molecules are present- the original molecule, and a newly synthesized DNA molecule.

Which of the following are required for DNA replication by DNA polymerase?

A. Template strand
B. Short, complementary primer strand
C. 5'-dXTPs
D. 3'-dXTPs
E. Answers (A) and (C)
F. Answers (A) and (D)
G. Answers (A), (B), and (C)

H. Answers (A), (B), and (D)

Which of the following are reasons why DNA replication must be discontinuous?

A. The complementary strands have opposite polarity
B. Only 5'-dXTPs are available in cells
C. DNA polymerase only adds 5-'dXTPs to 3'-OH ends
D. All the above
E. Answers (A) and (C)
F. Answers (B) and (C)

G. Answers (A) and (B)

Which of the following are roles of RNA polymerases in DNA replication?

A. RNA polymerase (primase) initiates replication at the origin
B. RNA polymerase synthesizes the primers for Okazaki fragments
C. Both (A) and (B)

D. Neither (A), nor (B)

Which of the following statements describes the activity of DNA polymerase?

A. DNA polymerase adds 3’-dXTPs to the 5’-OH terminus of the primer
B. DNA polymerase adds 5'-dXTPs to the 3’-OH terminus of the primer
C. DNA polymerase adds 5’-dXTPs to the 3’-phosphate terminus of the primer
D. DNA polymerase adds 3’-dXTPs to the 5’-phosphate terminus of the primer

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