A 4 week old boy was brought into see you by his parents because of a large axillary abscess. His parents, who are healthy, tell you that he previously had other smaller abscess that appeared to have healed on their own. Over the next few months the child was brought in two more times with similar abscesses. Analysis of his white-cell count showed that 90% were neutrophils. His neutrophils moved and phagocytosed Staphylococcus aureus normally; however, they showed impaired intracellular killing of Staphylococcus. Further tests on this boy showed that his polymorphs failed to consume oxygen or to produce hydrogen peroxide during phagocytosis. 1. Based on this information, what is the probable diagnosis for this child's condition?
2. please explain to the parents how their child could have this condition?
3. Is there a cure? If not, what will you tell the parents about the prognosis for their child?
A 4 week old boy was brought into see you by his parents because of a large axillary abscess. His parents, who are healthy, tell you that he previously had other smaller abscess that appeared to have healed on their own. Over the next few months the child was brought in two more times with similar abscesses. Analysis of his white-cell count showed that 90% were neutrophils. His neutrophils moved and phagocytosed Staphylococcus aureus normally; however, they showed impaired intracellular killing of Staphylococcus. Further tests on this boy showed that his polymorphs failed to consume oxygen or to produce hydrogen peroxide during phagocytosis. 1. Based on this information, what is the probable diagnosis for this child's condition?
2. please explain to the parents how their child could have this condition?
3. Is there a cure? If not, what will you tell the parents about the prognosis for their child?
