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A teenage male had a history of colitis, most likely Crohn’s disease. He had difficulty controlling his disease with medical management and had been treated with parenteral nutrition and pain medication. He attends high school and is socially adjusted, even though his illness has caused him to be small in stature. He lives with his mother, who works for a veterinarian. The reason for this admission was abdominal discomfort and erythema at the exit site and along the tunnel of his central line. Blood cultures were collected, and both the blood cultures and his catheter tip cultures grew a catalase-positive, gram-positive cocci. The coagulase tube test was positive, but the slide and latex test for coagulase were negative

QUESTIONS

What further biochemical testing would you perform?

Because of the difficulties in expression of the mecA gene product in staphylococci, studies have been done to determine which antimicrobial agent best induces the microorganism to produce PBP2a. After extensive studies with many challenge strains, which antimicrobial agent was found to best predict the susceptibility or resistance to the penicillinase resistant penicillins?

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Beverley Smith
Beverley SmithLv2
28 Sep 2019

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