Blood pressure is influenced by both genetic and environmental factors. In a study of sibling pairs, both siblings of the pair had high blood pressure in 30% of the pairs. What is the heritability of this trait? SHOW ALL WORK!

I've seen the other answers to this same question and they make no sense to me! Please help me by showing all work and determining what the heritability of this blood pressure trait is. If you could explain it that would be AMAZING.

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Reid WolffLv2

28 Sep 2019

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Blood pressure is influenced by both genetic and environmental factors. In a study of sibling pairs, both siblings of the pair had high blood pressure in 30% of the pairs. What is the heritability of this trait? SHOW ALL WORK

ceruleanlion180

SCENARIO: During medical examinations of the poor, a nurse observes that several of the patients smoked and had high blood pressure. The nurse reviewed the related literature and found that smoking and high blood pressure shared a positive relationship. The nurse believed that poverty may have an additive influence to smoking relationship with high blood pressure. The nurse decided to conduct an investigation into this relationship. The nurse collected data on over 100 patients. The data collected were blood pressure (high or low), smoking (currently smoking, not currently smoking but smoked in the last year, never smoked), and poverty. Poverty was measured as a self report by the patient. The nurse used a partial bivariate correlation to analyze the data. The nurse found that while controlling poverty, that smoking still had a positive relationship with high blood pressure (worth 50 points).

Questions:

What kind of study is this according to the methodology used? Justify your choice.

Write a research hypothesis/hypotheses or question(s) for this study and identify the independent and dependent variables in the study.

Critique the internal and external validity of the study as it is designed.

Critique the data analysis used in the study.

If you were going to conduct this study, how would you redesign to enhance its validity and at the same time make it reasonable to conduct? In your redesign be sure to address the appropriateness of using self-report poverty and the statistical procedure(s) that you would use to analyze data.

2] Craniofacial microsomias syndrome (CMS) presents with a spectrum of abnormalities mainly in the skull and face. It is characterized by facial asymmetries on the left and right sides in size and shape. This can cause dental problems as well as defects in feeding, speech and breathing in severe cases.

Imagine that you were to be presented with the following study of twins with this syndrome where the pair was identified by finding an CMS child: 20 pairs of identical twins were reported, where both twins showed CMS, and in all cases the parents were normal, while in 18 pairs of dizygotic twins, 5 of the twin pairs had both twins affected.

2b) Do these data allow you to postulate anything about whether CMS is genetic and if so what the mode of inheritance might be?

2c) Do you agree with the assertion that there must be families where both parents are carriers of CMS that have identical twins but the twins are unaffected? Why are there no families with identical twins where one or more of the children are unaffected?

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