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Hemophilia A is a recessive X-linked genetic disorder. A healthywoman known to not carry the hemophilia allele has four sons andfour daughters with a man with hemophilia A. What proportion of herchildren are expected to suffer from hemophilia A?

Select one:

a. all of the sons and daughters

b. half of the sons and all of the daughters

c. all of the daughters and none of the sons

d. all of the sons and none of the daughters

e. none of the sons or daughters

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Reid Wolff
Reid WolffLv2
28 Sep 2019
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Related questions

A woman, Melanie, and a man, Allan, who are both carriers for phenylketonuria (a rare autosomal recessive disease) have two daughters, Jessica and Andrea, and two sons, Kyle and James. None of Melanie and Allan's parents, or their siblings, had phenylketonuria. However, both of their sons have the disease.
Answer questions 1 to 8 based on this scenario. Please use P to indicate the dominant allele for this condition and p to represent the recessive allele.

1) What are Melanie and Allan's genotypes?

2) Based on the scenario given, what are the most likely genotypes of Melanie's parents and of Allan's parents?

3) What are the genotypes of each of their daughters? What are the genotypes of their sons?

4) What percentage of Melanie's eggs will carry the phenylketonuria allele? What percentage of Allan’s sperm will carry the phenylketonuria allele?

5) Melanie is pregnant and she and Allan have just found out the sex of the fetus is male. What is the probability the fetus is carrying two copies of the recessive phenylketonuria allele, and thus will be affected with the disease?

6) Among Melanie and Allan's four children, how does the observed frequency of affected children compare to the expected frequency? Does the observed result go against the concepts of Mendelian genetics?

A woman with normal blood clotting ability whose father was ahemophiliac and whose mother was normal with no family history ofhemophilia marries a man whose blood has normal clottingability.

a. What is the probability that their first child will be adaughter with hemophilia? Round your answer properly to 3 decimaldigits.

b. What is the probability that their first child will be a sonwith hemophilia? Round your answer properly to 3 decimaldigits.

c. A man who has an X-linked dominant allele will pass it on to(pick all that apply)
All of his daughters
Half of his daughters
Half of his sons
All of his sons

1. A colorblind woman marries a normal man. Which of thefollowing is true of their children?
a. all will be colorblind
b. all daughters will be normal and all sons will be carriers
c. all daughters will be colorblind and all sons will benormal
d. all daughters will be heterozygous and all sons will becolorblind
e. it is impossible to predict with any reasonable degree ofcertainty

2. Cleft chin is an autosomal dominant trait. A man with a cleftchin marries a woman with a round chin. What proportion of theirfemale progeny will show the trait?
a. 0%
b. 25%
c. 50%
d. 75%
e. 100%

3. Which of the following statements is false?
a. individuals with the same phenotype might have differentgenotypes
b. matings between individuals with dominant phenotypes cannotproduce offspring with recessive phenotypes
c. matings between individuals with recessive phenotypes usually donot produce offspring with dominant phenotypes
d. individuals with the same genotype might have differentphenotypes.
e. all the above are correct choices

4. True or False
a. DNA is composed of 4 different types of nucleotides T/F?
b. in the DNA of every species, the amount of adenine presentalways equals the amount of thymine, and the amount of cytosinealways equals the amount of guanine T/F?
c. in a nucleotide, the phosphate group is attached to thenitrogen-containing base, which is attached to the 5 carbon sugarT/F?
d. Watson and Crick built their model of DNA in the early 1950sT/F

5. MATCHING - each choice can be used more than once.
a. ribosomal RNA
b. DNA
c. mRNA
d. tRNA
e. RNA polymerase
-carries the genetic code sequence
-joins up with amino acids
-attaches the specific amino acids
-contains no uracil
-has anticodons
-determines amino acid sequence
-reads the codons
-contains codons
-has 2 polynucleotide chains
-has deoxyribose sugar
-makes RNA molecules in the nucleus

6. The number of base pairs in the human genome is about:
a. 1 million
b. 1 trillion
c. 10 billion
d. 75 billion

7. Pyrimidines are
a. single ringed
b. triple ringed
c. double ringed
d. none of these

8. Adenine is
a. double ringed
b. single ringed
c. a straight up chained carbon compound
d. a phospholipid

9._______ is the enzyme which puts together the correct DNA basesequence
a. DNA polymerase
b. RNA polymerase
c. helicase
d. adenine

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