FMRP activity is strongly controlled by its phosphorylation status. Which of the subsequent statements are true?

Question options:

a)
None of the listed statements are true

b)
PP2A phosphatase will dephosphorylate FMRP to associate it with its target mRNAs to trigger their immediate translation.

c)
S6K1 kinase will phosphorylate FMRP to dissociate FMRP from target mRNAs to inhibit translation.

d)
phosphorylation of FMRP by S6K1 kinase will trigger ubiquitination of FMRP and its degradation, thereby allowing target RNA translation.

Question

FMRP activity is strongly controlled by its phosphorylation status. Which of the subsequent statements are true?

Question options:

a)	None of the listed statements are true

b)	PP2A phosphatase will dephosphorylate FMRP to associate it with its target mRNAs to trigger their immediate translation.

c)	S6K1 kinase will phosphorylate FMRP to dissociate FMRP from target mRNAs to inhibit translation.

d)	phosphorylation of FMRP by S6K1 kinase will trigger ubiquitination of FMRP and its degradation, thereby allowing target RNA translation.

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