Colorblindness and hemophilia A both recessive traits. The two genes are located 10cM apart on the X chromosome. A phenotypically normal man with no family history of either disease is married to a phenotypically normal woman, whose father has hemophilia A and mother is colorblind. If this couple has a son..

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what is the probability that he will have neither hemophilia nor colorblindness?

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Keith LeannonLv2

29 Sep 2019

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A normal woman with a color-blind father married a normal man, and their first child, a boy, had hemophilia. Both color-blindness and hemophilia are due to X-linked recessive mutations, and the relevant genes are separated by 10 cM. This couple plans to have a second child. For each female and male, what is the probability that it will have hemophilia? color-blindness? both hemophilia and color-blindness? neither hemophilia nor color-blindness?

1. If you had a fruitfly with phenotype A, what test would you make to determine if it was Aa or AA? Explain the different outcomes expected if the fly in question is AA or Aa.

2.The sex of birds, some insects, and other organisms is determined by a ZW chromosomal arrangement in which the males have like sex chromosomes (ZZ) and females are ZW (similar to XY in humans). Assume that a recessive lethal allele on the Z chromosome causes death of an embryo in birds. What sex ratio would result in the offspring if a cross were made between a male heterozygous for the lethal allele and a normal female?

3.A recessive gene for red-green color blindness is located on the X chromosome in humans. Assume that a woman with normal vision (her father is color-blind) marries a color-blind male. What is the likelihood that this couple's first son will be color-blind?

4. One form of hemophilia is caused by a sex-linked recessive gene. Assume that a man with hemophilia marries a phenotypically normal woman whose father had hemophilia. What is the probability that they will have a daughter with hemophilia? (Note: In this problem, you must include the probability of having a daughter in your computation of the final probability.)

5. One form of hemophilia is caused by a sex-linked recessive gene. Assume that a man with hemophilia marries a phenotypically normal woman whose father had hemophilia. What is the probability that their first son will have hemophilia?

amethystgnat408

Genes for color blindness and hemophilia are linked on the X-chromosome in humans with a recombination frequency of 30 %. A woman whose father was a color blind hemophiliac and mother was normal with no history of color blindness and hemophilia wants to have children. The prospective father is normal with no history of either color blindness or hemophilia in his family. What is the probability that she will have a normal child?

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