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. We observed that cancer is the combination of variousmutations in individuals and that two people with the same cancertype can have very different mutations which cause it to occur.Which statement(s) below are TRUE?

A. Cancer is caused by multiple “hits” or mutations.

B. All cancers are caused by a mutation in TP53.

C. Cancer can be caused by multiple mutations in processesregulating mitosis.

D. Cancers can be caused by chromosomal changes (deletions,insertions, viruses) as well as small point mutations.

E. Cancer is the leading cause of death in the UnitedStates.

F. Exposure to mutation-inducing chemicals (mutagens) increasesthe number of “hits” a person might have and thus increase theirrisk of cancer.

G. Cancer can be caused by multiple mutations in processesregulating cellular differentiation (growth and maturity).

H. Cancer can be caused by chromosomal maintenance mutations(telomere shortening, epigenetic changes, DNA Polymerase defects,etc.)

I. Cancer can be caused by mutations that increase cell deathpathways.

J. Cancer can be caused by mutations that decrease cell deathpathways. K. Checks and balances in multiple pathways ensure thatone mutation does not cause cancer to develop in humans.

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Jarrod Robel
Jarrod RobelLv2
30 Sep 2019
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