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21 Feb 2019

A male mouse that is homozygous recessive for the BIG gene (bb) is crossed to a homozygous dominant female mouse (BB). The offspring are all small.
In a reciprocal cross, a homozygous recessive female mouse (bb) is crossed to a homozygous dominant male mouse (BB). This time the offspring are all big.

(a) What are the genotypes of the offspring in each cross?

(b) These crosses demonstrate which inheritance pattern: x-linked inheritance, imprinting, dosage compensation, or cytoplasmic inheritance?

(c) Explain why the phenotypes of the offspring are different in the two crosses.

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