NUR 326 Lecture Notes - Lecture 10: G0 Phase, Lung Cancer, Miosis

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* zarcone will never ask which group of anticancer drugs would be used for a specific type of cancer. Just know the drug, it is an anticancer medication, and the specifics to that drug that you will have to worry about (bolded in red). Indication: an immunosuppressive agent for breast, lung, ovarian, hodgkin"s disease, leukemia"s and lymphomas: inhibition of protein synthesis through interference with dna replication by alkylation of. Side effects: nausea, vomiting, diarrhea, weight loss, hematuria, alopecia, impotence, sterility, ovarian fibrosis, headache, dizziness, dermatitis. Adverse effects: hemorrhagic cystitis, secondary neoplasm, bone marrow depression. Life-threatening: leukopenia, thrombocytopenia, cardio toxicity (high doses), hepatotoxicity (long- term) Avoid others with respiratory infections, report signs of infection immediately. Indication: treatment of breast, bladder, ovarian and lung cancers, leukemia"s, lymphomas, soft tissue and bone sarcoma: inhibits dna and rna synthesis, has immunosuppressive activity. Adverse effects: esophagitis, anemia, hyperpigmentation of nails, tongue and oral mucosa (more often in african americans)

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