NUR 326 Lecture Notes - Lecture 9: Cytochrome C Oxidase Subunit Ii, Hives, Salicylic Acid
Document Summary
Chapter 25: anti-inflammatory drugs chemical mediators accumulate at the injured tissue or infection site: when the inflammatory process occurs, a vascular reaction takes place in which fluid; elements of blood, leukocytes (white blood cells), and. They cause vasodilation, relaxation of smooth muscle, and an increased sensitization of nerve cells. If inhibited, there is an increased risk for ulcers, while decreasing pain and inflammation: cox-2 triggers inflammation and pain. If inhibited, there is a decrease in pain and inflammation without inhibiting stomach protection. Anti-inflammatory agents also relieve pain (analgesic), reduce elevated body temperature (antipyretic), and inhibit platelet aggregation (anticoagulant): nsaids (nonsteroidal anti-inflammatory drugs) have potent anti-inflammatory effects that mimic the effects of corticosteroids, but they are not chemically related to corticosteroids. Indication: reduce pain and inflammatory symptoms, decrease body temperature (antipyretic fever reducer), inhibit platelet aggregation: inhibits cox 1&2 worry about stomach ulcers, one of the most acidic drugs to the stomach.