Biology 2581B Lecture 10: Lecture 10: Mapping PPT + NOTES
10 Feb 2016
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When you get one, you often get other close on a chrome (linked hemo and. Indicates hemo a and b are not the same and not closely linked different location colour bilnd) Victoria was a carrier had many kids. Some of her daughters were carriers, and the men were hemo. When you have wound, red blood cells go through. Fibrinogen causes cross links and forms clots (part of process requires factor 8) Tracked factors to see if people had factors or nah. All of them had everything except factor 8 (hemo patients) Looked for coding sequence for factor 8 did not know what it looked like. But had protein so they purified the protein. Obtained amino acid sequence of this protein but only bits and pieces. Now you can determine what codon should be at a specific place reverse. But there are aa coded by more that 1 codon have to guess (wobble)
