BIO230H1 Lecture Notes - Lecture 20: Dna-Binding Domain, Nitric Oxide, Alarm Clock

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22 Dec 2019
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BIO230H1 Full Course Notes
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BIO230H1 Full Course Notes
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Eventually, b comes back to inhibit a. Alarm clock; over time, they sound quieter if we stay asleep. Made by the deamination of arginine by no synthase (nos) Acts locally 5-10 second half life. Targets smooth muscle and other target cells. Nitroglycerine used to treat heart pain; it is converted to no, relaxes blood vessels and reduces the workload on the heart. Steroid hormones made from cholesterol; affects sexual characteristics and metabolism. Thyroid hormones made from tyrosine; increases metabolic rate. Retinoids made from vitamin a; regulates development. Binding site for small hydrophobic molecule (ligand binding domain) & for. Through plasma membrane channels largely talking about ions. Overall, the cell is neutral; however, across the membrane, there will be differences. Based on electrochemical gradients and ion diffusion ie. passive transport. Signal the single-cells paramecium to reverse its movement upon collision. Downstream of plasma membrane gpcrs eg. protein signalling (however, there can be other methods as well)