BIO230H1 Lecture Notes - Lecture 4: Transferase, Acetyltransferase, Acetyl Group
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BIO230H1 Full Course Notes
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Mrna: messenger rna ( translation) rrna: ribosomal rna (form ribosomes) trna: transfer rna (link b/w mrna & amino. Mirna: micro rna (selectively blocks translation of mrna) sirna: small interfering rna (selectively directs degradation of mrna) Other non-coding rna telomere synthesis, x-chromosome inactivation, transport of proteins into the. Rna polymerase ii (all protein-coding genes, sirna, mirna) Promotors: contain tata box (often, not always) Tf2d (transcription factor 2 d: tbp subunit: recognizes tata box, taf subunit: regulates tbp-dna binding. Tf2b: positions rna polymerase at transcription start site. Tf2h: splits apart dna helix, phosphorylates rna polymerase (pushes it to start transcription) Specific combination of proteins = one gene regulatory protein can perform different functions. The coactivator / corepressor does not bind directly on the dna- assemble on dna-bound gene regulatory proteins. Mediator: protein mediating regulatory proteins & rna polymerase activity. Holds the regulatory proteins together so rna.
