BIOL 102 Lecture Notes - Lecture 3: Active Transport, Differential Centrifugation, Glycosylation

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Phospholipids in plasma membrane move within bilayer. If unsaturated, kink pushes them apart/increase fluidity. Temperature if too solid lose ability to service semipermeable carriers ion leakage. Some proteins will be held in place with the cytoskeleton. Approximately 25% of all genes encode membrane. Integral is anchored to membrane or on other side. 70% drugs target membrane proteins message to nucleus proteins. Conformational changes allow for information to be passed. More polarity and larger or a combo, permeability / ability to go through the membrane is impeded. Because of semipermeable membrane able to hsve gradients. Water moves down gradient with no energy expended diffusion of two solutes high permeable things diffuse across the membrane wirh no help. Carrier proteins undergo a subtle change in shape translocates solute binding site. Each is specific to molecule/class and will be. Water diffuses through membranes to balance solute concentration. Osmotic pressure can result if solutes are impermeable cell shrinks/swells.

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