BIOL 102 Lecture Notes - Lecture 6: Peripheral Membrane Protein, Transmission Electron Microscopy, Lipid Bilayer
7 Dec 2016
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Document Summary
Phospholipids are amphipathic: hydrophobic faces in (avoids water, hydrophilic faces out (faces water) Also contains proteins/carbohydrates relative amount of each vary. Leaflets are not symmetrical, nor are the proteins: covalent modification to help it function on its leaflet side. Phospholipids are free to rotate around the axis without flip with some facilitated help input of energy. Lipids are free to diffuse around, not swap sides. Membranes that become too fluid or too rigid cannot function. Membrane becomes too solid too leaky, ions will just diffuse down the gradient and homeostasis in lost. Adaptions to these changes of environment: kink in the acyl trail double bond. Cannot pack together as tightly because of the kink which allows fluidity, desaturation. Temperature goes up too fluid, saturation occurs to remove the double bonds, put in a hydrogen, and allows the phospholipid tails to interact more tightly more rigid.
