BIOL 102 Lecture Notes - Lecture 6: Peripheral Membrane Protein, Lipid Bilayer, Phospholipid Scramblase
15 Oct 2014
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Document Summary
Membrane structure and transport mid term is going to be on the tuesday on the 7th week: basic framework is phospholipid bilayer, phospholipids are amphipathic. Hydrophilic region faces out: also contain proteins & carbohydrates. Cytosol two leaflets, inner and outer, not symmetrical. Cytosolic leaflet are not always lipid bilayers, their very complex mosiac- lots of different components and they are semi-fluid. Factors affecting fluidity: length of fatty acyl tails. Shorter acyl tails are less likely to interact, which makes the membrane more fluid: presence of double bonds in the acyl tails. Db creates kink tail, making it more difficult for neighboring tails to interact = more fluid: presence of cholesterol (animals) Proteins bound to membranes: integral membrane proteins. Noncovalently bound to integral membrane proteins or to the polar head groups of pls. Proteins are a critical aspect of membrane structure and function.
