NEUR30004 Lecture Notes - Lecture 29: Pain Management, Neuropathic Pain, Action Potential
20 Oct 2020
School
Department
Course
Professor
Document Summary
Readings: any good neuroscience text and primary literature. Pain is an unpleasant sensoryor emotionalexperience associated with actualor potentialtissue damage (or described in terms of such damage) International association for the study of pain subcommittee on taxonomy, 1986. Pain: protective sensation (mechanism, awareness of damage occurring or about to occur, note that there are multiple dimensions to pain: Perception of pain is dependent upon: cellular damage, sensory receptor stimulation and input to cns, spinal processing, ascending and descending neural pathways, subcortical and cortical sensory processing sites, note, there is no designated pain nucleus" in the brain. Instead, the multiple dimensions of pain depend upon complex higher brain processing. Nociceptors = free nerve endings in tissues arising from nociceptive sensory neurons. Found in spinal and some cranial nerves (notably trigeminal) e. g. corneal nociceptors. Contrast pain from exteroceptive versus interoceptive stimuli not show are visceral innervation maps.
