BIOC 3110 Chapter Notes - Chapter 19: Succinyl Coenzyme A Synthetase, Succinyl-Coa, Citric Acid Cycle

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5 Oct 2016

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The function of the citric acid cycle is the harvesting of high-energy electrons from carbon fuels. Citric acid cycle 2 stages: stage 1: oxidation of the two carbon acetyl coa to gather energy. Fatty acids, glucose and amino acids enter cycle as acetyl coa. The mechanism of citrate synthase prevents undesirable reactions: this is the initiation step of the citric acid cycle, so side reactions must be minimized, structure of enzyme: Isocitrate is oxidized and decarboxylated to alpha- ketoglutarate: first oxidation reduction step, isocitrate is oxidized, and nad+ picks up a h, this forms an unstable intermediate (oxalosuccinate), so it spontaneously loses a co2 to form alpha-ketoglutarate. At end of stage 1: 2 c atoms entered, 2 co2 have left, and 2. Nadh have left, and end product is succinyl coenzyme a (4c: stage 2: regeneration of oxaloacetate and harvesting energy rich electrons. A compound with high phosphoryl-transfer potential is generated from succinyl coenzyme a.

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Question 48

Soccer (assuming field player) is a sport which is 90% aerobic.

True

False

Question 50

Glucose is necessary for fatty acid oxidation because...

		its derivative, pyruvate, is condensated with carbonic acid to form oxaloacetate, which in turn is a necessary carbon compound in the citric acid cycle
		it is needed to convert fatty acids to fatty acyl-CoA which in turn is oxidized to acetyl CoA
		glucose is decarboxylated into cytochrome oxidase which is a necessary intermediate in the citric acid cycle
		its derivative, acetyl CoA, is condensated with carbonic acid to form lactase, which in turn is a necessary carbon compound in the citric acid cycle

Question 51

In aerobic ATP production, the role of oxygen is to...

		to keep the electron transport chain operational
		to accept electrons from the 3rd cytochrome and thereby oxidizing it so it can accept new electrons
		act as a oxidizing agent by accepting electrons from the electron transport chain and combining with hydrogen ions (protons)
		all of the above

Question 52

The primary purpose of the citric acid cycle is...

aerobic glycolysis

gluconeogenesis using lactate

the decarboxylation of carbon compounds to produce NADH.

the shuttling of hydrogen ions through the inner mitochondrial membrane

Question 55

Which of the following is the best predictor of marathon running performance?

	A.	Maximal rate of pyruvate oxidation
	B.	Maximal rate of lactate formation
	C.	Amount of adipose tissue triglycerides
	D.	Pre-race blood glucose concentration

emeraldfly517

Question 18

The process that forms new glucose in the liver is called ...

	A.	glycogenolysis
	B.	Krebs cycle
	C.	lipolysis
	D.	gluconeogenisis
	E.	oxidative phosphorylation

Question 57

A person exercises in their âfat burning zoneâ for 4 hours at 35% VO₂peak. The O₂ cost of exercise at that work rate is 0.5L/minute. Following exercise the subject rewards himself with an ice-cream sundae (700kcal). The following statement is true(assume 5kcal/lit of O₂):

	A.	The subject is in neutral energy balance
	B.	The subject consumed fewer calories than they expended during exercise
	C.	The subject consumed more calories than they expended during exercise
	D.	Canât say

Question 52

The primary purpose of the citric acid cycle is...

		aerobic glycolysis
		gluconeogenesis using lactate
		the decarboxylation of carbon compounds to produce NADH.
		the shuttling of hydrogen ions through the inner mitochondrial membrane

Question 51

In aerobic ATP production, the role of oxygen is to...

		to keep the electron transport chain operational
		to accept electrons from the 3rd cytochrome and thereby oxidizing it so it can accept new electrons
		act as a oxidizing agent by accepting electrons from the electron transport chain and combining with hydrogen ions (protons)
		all of the above

Question 50

Glucose is necessary for fatty acid oxidation because...

		its derivative, pyruvate, is condensated with carbonic acid to form oxaloacetate, which in turn is a necessary carbon compound in the citric acid cycle
		it is needed to convert fatty acids to fatty acyl-CoA which in turn is oxidized to acetyl CoA
		glucose is decarboxylated into cytochrome oxidase which is a necessary intermediate in the citric acid cycle
		its derivative, acetyl CoA, is condensated with carbonic acid to form lactase, which in turn is a necessary carbon compound in the citric acid cycle

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BIOC 3110 Chapter Notes - Chapter 19: Succinyl Coenzyme A Synthetase, Succinyl-Coa, Citric Acid Cycle

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