Log in
HomeClass Notes1,200,000US530,000

BIOC 3110 Lecture Notes - Lecture 18: Pyruvate Dehydrogenase, Acetyl-Coa, Pyruvic Acid

18 views3 pages
lavendergnu459
6 Oct 2016
School
University of Iowa
Department
Biochemistry
Course
BIOC 3110
Professor
marcwold

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

How is carbon coming from glycolysis introduced into cac: pyruvate acetyl coa, acetyl coa can come directly from pyruvate, or fatty acids and amino acids, pyruvate has to be transported from cytoplasm to inner matrix. Mitochondria has outer membrane (easily permeable) and inner membrane (not permeable unless channel) Pyruvate must get into matrix to mitochondria to change it into acetyl coa, using a channel. What would be alternative to connecting to the cac: anaerobic-lactic acid or alcohol fermentation, must decide whether to generate energy or store reserves to make energy later. How does compartmentalization of glycolysis and the cac affect these pathways: to get pyruvate into mitochondria we need transporter (pyruvate transporter, then we must turn pyruvate into 2c molecule. What is the role of pyruvate dehydrogenase: allows sequential transfer because everything is so close, pyruvate dehydrogenase complex turns pyruvate (3c) into 2 c acetyl. 5 cofactors catalytic-tpp, lipoamide, fad stiochemiometric- coa, nad- travel along with reacts.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents

BIOC 3110 Lecture Notes - Lecture 28: Methylene Group, Aspirin, Acetaldehyde
lavendergnu459
BIOC 3110 Lecture Notes - Lecture 16: Blood Sugar, Fructokinase, Glycogen
lavendergnu459
BIOC 3110 Lecture Notes - Lecture 30: Glutamine Synthetase, Carbamoyl Phosphate, Glutamate Dehydrogenase
lavendergnu459

Related Questions

1) In Eukaryotic cells, Glycolysis occurs in the __________,Pyruvate Oxidation and the Citric Acid Cycle occur in the ________,and the electron transport chain is in the _____________.

a) Mitochondrial matrix; Mitochrondrial inner membrane;Cytoplasm

b) Cytoplasm; Mitochrondrial inner membrane; Mitochondiralmatrix

c) Mitochrondrial inner membrane; Cytoplasm; Mitochondrialmatrix

d) Cytoplasm; Mitochondrial matrix; Mitochrondrial innermembrane

e) Mitochrondrial inner membrane; Mitochondrial Matrix;Cytoplasm

2) We can detect tyrosinase among thousands of other proteins ina mushroom extract (in a solution or in-gel) because:

a) Its bigger than other proteins

b) Its smaller than other proteins

c) Its more charged than other proteins

d) It reacts with a specific substrate to produce a coloredproduct

e) It converts a specific colored substrate to a colorlessproduct

3) The highest energy carrier (transfer molecule) in cellsis:

a) NADH

b) FADH2

c) ATP

d) GTP

e) Acetyl- coA

1.) Certain complexes of the mitochondrial electron transport chain pump protons. Which of the following BEST describes the movement of protons in this situation?

a.) across the outer mitochondrial membrane, from the cytoplasm to the intermembrane space

b.) across the outer mitochondrial membrane, from the intermembrane space to the cytoplasm

c.) across the inner mitochondrial membrane, from the intermembrane space to the matrix

d.) across the inner mitochondrial membrane, from the matrix to the inter membrane space

2.) Which regulatory mechanism is activated when the overall energy availability of a cell is high?

a.) Citrate inhibits phosphofructokinase-1.

b.) ADP up-regulates phosphofructokinase-1.

c.) ATP inhibits phosphofructokinase-1.

d.) AMP up-regulates phosphofructokinase-1.

3.) Electron carriers are oxidized during which of the following reactions?

a.) glycolysis

b.) citric acid cycle

c.) electron transport chain

d.) the conversion of pyruvate to acetyl coA

e.) all of the above

_____What is added to a molecule such as ADP when it is phosphorylated?

_____ An anaerobic process in which pyruvate is converted to lactate

_____ A biochemical process that breaks down food molecules to produce other molecules for cellular maintenance.

_____What is the final end product of Glycolysis?

_____ Refers to the potential energy provided by a large hydrogen-cation concentration gradient, and it’s movement across a biological membrane during chemiosmosis.

_____ A molecule that transfers or shuttles electrons during redox reactions.

_____ An organism that can survive in the presence or absence of oxygen.

_____ A type of enzyme that teams with NAD+ to remove hydrogen atoms with their electrons.

_____ The loss of electrons from one molecule to another.

_____ A process in which ATP is produced using the energy stored in concentration gradients.

_____ The products produced during a biochemical reaction that fall between the starting molecule and the end product.

_____ Biochemical process in which a glucose molecule is degraded to two pyruvates.

_____ Short for “reduction/oxidation” reactions

_____How many pyruvate molecules are produced from a single Glyceraldehyde 3-phosphate?

_____ The formation of ATP occurring when an enzyme transfers a phosphate group from an organic molecule to ADP.

_____ Organisms that will die in the presence of oxygen.

_____ A term referring to the presence of oxygen.

_____ A series of electron-carrier molecules that shuttle electrons during the redox reactions that release energy used to make ATP.

_____ A biochemical process in which pyruvate is produced without the presence of oxygen.

20._____ The metabolic cycle that is fueled by Acetyl CoEnzyme A; occurs in the matrix of the mitochondria and supplies most of the NADH molecules that carry energy to the electron transport chain.

_____What is the chemical formula for Cellular Respiration?

_____What environmental condition is necessary for Anaerobic Respiration to occur?

_____Where does the Electron Transport Chain occur in the mitochondria?

_____Where does Glycolysis occur in a cell?

_____ An anaerobic process in which CO2 is released as a byproduct and ethanol is produced as a product.

_____Where does the Krebs cycle occur in the mitochondria?

_____ The gain of electrons from one molecule to another.

_____ A high-energy fuel molecule that begins the Citric Acid Cycle.

_____What condition is necessary of Aerobic Respiration to occur?

_____ A term referring to the absence of oxygen.

_____What compound is derived from B vitamins, and helps the Acetyl portion of Acetyl CoA into the Krebs Cycle?

_____What is the name of the molecule that channels protons, providing the energy necessary to phosphorylate ADP to ATP?

_____In the blank, write the number of ATP’s that can be synthesized from 3 NADH molecules.

_____In the blank, write the number of ATP’s that can be synthesized from a single FADH2 molecule.

_____What is the final electron acceptor in cellular respiration?

_____What molecule is regenerated during the process of the Krebs Cycle?

_____What enzyme is used to catalyzed the reaction that occurs during the formation of Acetyl CoA?

_____How many pyruvates are produced from a single glucose molecule?

_____How many Acetyl CoA molecules are produced from a single glucose molecule?

_____What is the reduced form of Nicotinamide Adenine Dinucleotide?

_____What is the oxidized form of Flavin Adenine Dinucleotide?

42._____ A membrane protein that is used in conjunction with chemiosmosis to produced ATP.

I know that this alot of questions, but it's kinda a last ditch effort. these are the last 42 definitions i have left to answer out of 500 question for my final exam study guide. so whatever help i can get is fine. No explanations needed just what each definition is explaining and thanks in advance ladies and gentlemen.