BIOCHEM 423 Chapter 8.8: BIOCHEM 423 Chapter 8.: Biochem423 8.8
7 Dec 2018
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A regulation of enzyme activity is essential for the ettiuent and ordered how of metabolism. The ettiuenues with which individual enzymes operate must be controlled in a manner that reflects the availability of substrates the utilization of products and the overall needs of the all a substrate - level. Control v= vet ed linear relationship . intracellular concentrations ot many metabolites uz well below saturating concentrations for the enzymes that. Inhibition the reaction product binds the enzyme active site and therefore acts as a competitive inhibitor. E leads to a decrease in its rate of production . end p product. A activation or inhibition ot enzymes that catalyse reactions. At key control points in a pathway typically occurs through a allostenc mechanism . a aho stent. Atlostenc enzymes are frequently multi subunit proteins with multiple active sites. They exhibit regulation of their activity by other , ettector molecules.
