BIOCHEM 420 Chapter Notes - Chapter 8: Chemical Equation, Hydrolysis, Beck

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Chapter 3 : the energetics of life: 4 free energy in biological systems. Every biochemical process must be a thermodynamically favorable process. Intrinsically unfavorable processes can be made thermodynamically favorable by coupling them to strongly favorable reactions (cid:8869) a 2b. If the cell can manage to couple these two reactions, the ag " for the overall process will be the algebraic sum of a g " for the individual reactions. Driving an unfavorable process by coupling it to a favorable one requires the availability of compounds that can undergo reactions with large negative free energy changes (cid:8869) thought of as energy transducers in the cell. Phosphoryl group transfer potential correlated with -ag " of hydrolysis. * the phosphoryl group transfer potential is shows which compounds can phosphorylate others under standard conditions. Atp can act as a versatile phosphoryl group transfer agent through coupled reactions. Electron transfer occurs via a series of linked oxidations and reductions, or " redox reactions.

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