BSC 2010 Chapter Notes - Chapter 3: Thymine, Pentose, Peptide

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The nucleic acids, dna and rna, are used mainly to store, transmit, and express hereditary (genetic) information. A nucleotide consists of one to three phosphate groups, a pentose sugar (ribose in rna and deoxyribose in dna) and a nitrogen-containing base. In dna, the nucleotide bases are adenine (a), guanine (g), cytosine (c), and thymine (t). The nucleotides are joined by phosphodiester bonds between the sugar of one and the phosphate of the next. Rna is usually single-stranded, whereas dna is double-stranded. Complementary base pairing, based on hydrogen bonds between a and t, a and u, and. G and c, occurs in rna and dna. In rna the hydrogen bonds result in a folded molecule; in dna the hydrogen bonds connect two antiparallel strands into a double helix. Dna is expressed as rna in the process of transcription. Rna can then specify the amino acid sequence of a protein in the process of translation.

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