BSC 2010 Lecture Notes - Lecture 3: Dna Replication, Polynucleotide, Pentose

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Nucleic acids are polymers specialized for storage, transmission, and use of genetic information. Dna = deoxyribonucleic acid rna = ribonucleic acid monomers: nucleotides. Nucleotide: pentose sugar + n-containing base + phosphate group. Nucleotides bond in condensation reactions to form phosphodiester linkages. Nu(cid:272)lei(cid:272) a(cid:272)ids g(cid:396)ow i(cid:374) the 5 to 3 di(cid:396)e(cid:272)tio(cid:374). Oligonucleotides have about 20 monomers, and include small rna molecules important for. Dna and rna are polynucleotides, the longest polymers in the living world. Complementary base pairing: adenine and thymine always pair (a-t) cytosine and guanine always pair (c-g) There are so many hydrogen bonds in dna and rna that they form a fairly strong attraction, but not as strong as covalent bonds. Thus, base pairs can be separated with only a small amount of energy. Rna is usually single-stranded, but may be folded into 3-d structures, by hydrogen bonding. Folding occurs by complementary base pairing, so structure is determined by the order of bases.

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