BIO 117P Chapter Notes - Chapter Metzker: Gastroenterology, Subtypes Of Hiv, Dna Sequencing
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Metzker 2002 molecular evidence of hiv-1 transmission in a criminal case. Abstract a gastroenterologist was convicted of attempted second degree murder after injecting his former girlfriend with blood from a person with hiv type 1. This was the first time phyloge(cid:374)eti(cid:272) a(cid:374)alyses (cid:449)as used i(cid:374) a (cid:272)(cid:396)i(cid:373)i(cid:374)al (cid:272)ou(cid:396)t. they fou(cid:374)d that the patie(cid:374)t"s sequence and the (cid:448)i(cid:272)ti(cid:373)"s se(cid:395)ue(cid:374)(cid:272)e (cid:449)e(cid:396)e (cid:448)e(cid:396)y si(cid:373)ila(cid:396) poi(cid:374)ti(cid:374)g to(cid:449)a(cid:396)ds the likelihood of di(cid:396)e(cid:272)tio(cid:374) of transmission being from patient to victim. Dna testing has been very common in the judicial system. Not so common is the use of phylogeny to determine origin of hiv. This is because hiv mutates and changes rapidly: one of the most well-k(cid:374)o(cid:449)(cid:374) is the (cid:272)ase of the (cid:862)flo(cid:396)ida de(cid:374)tist(cid:863) This in fact was the first time that phylogenetic analysis has been used as evidence in a. Criminal investigation: tested the (cid:449)o(cid:373)e(cid:374)"s pa(cid:396)t(cid:374)e(cid:396)s fo(cid:396) hiv.
