BIO 211 Chapter Notes - Chapter 1: Aquaporin, Extracellular Fluid, Active Transport

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Water diuresis drinking large volumes of water will produce a large volume of hypotonic urine. Cortical portion of cd reabsorbs nacl, but it is impermeable to water. Salt is removed from the urine and water stays in the cd. Urine concentration may be as low as 50 mosm/l. Dehydration causes the urine to become scanty and more concentrated. High blood osmolarity stimulates posterior pituitary to release adh and then an increase in synthesis of aquaporin channels by renal tubule cells. More water is reabsorbed by collecting duct. Urine is more concentrated and can be up to 1200 mosm/l. The ability of kidney (collecting duct) to concentrate urine depends on salinity gradient in renal medulla. Multiplier - continually recaptures salt and returns it to extracellular fluid of medulla which multiplies the salinity in adrenal medulla. Countercurrent - because of fluid flowing in opposite directions in adjacent tubules of nephron loop.

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