BIO 1070 Chapter Notes - Chapter 14: Point Mutation, Mutation Rate, Base Pair

• School: St. John's University
• Department: Biology
• Course: BIO 1070
• Professor: Matteo Ruggiu

Document Summary

14. 1 mutation: gene mutations relatively small changes in the sequence of bases in a particular gene, timing of mutations has important consequences, point mutation affects only a single base pair within the dna, base substitution, addition/deletion of single base pair, effects of point mutations, silent mutation: causes no change. Addition or deletion: effects of mutations outside of the coding sequence of a gene, promoter: increases/decreases rate of transcription, operator site: alter regulation of transcription, splice sites: alter ability of pre mrna to be properly spliced, translational regulatory element: alter ability of mrna to be translationally regulated, intergenic region: not as likely to have an effect on gene expression, germ line cells that give rise to gametes such as sperm and egg cells, mutations in these have a 50% chance of being transmitted to offspring, somatic cells all cells of the body except the germ lines.