NFS 4271 Chapter Notes - Chapter ch 9: Ileum, Pyrosulfate, Itch
17 Sep 2017
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Amine group: pyrimidine group + thiazole ring linked by a methylene (ch2) bridge: sulfur and nitrogen containing. Thiamin pyrophosphate coenzyme form, two phosphates (thiamin. Helps body convert food into energy, and aids the function of the heart and diphosphate) tpp or tdp cardiovascular system and the brain and nervous system. Rda: men 19 and up 1. 2 mg, female 19 and up: 1. 1 mg, pregnancy: 1. 4 mg/day lactation: 1. 5 mg/day. Destroyed (primarily as methylene bridge) by heat and alkalinity: cooking thiamin-rich foods in water with promote loss of the vitamin. Exists in free (nonphosphorylated) form in plant foods. In animal foods, primarily as tpp, thiamin pyrophosphate (95%) Must be dephosphorylated in intestine to be absorbed as free thiamin intestinal phosphatases are responsible for digestion, specifically hydrolzing the phosphates from the di-, mono-, and triphosphates prior to absorption free thiamin is absorbed into intestinal cells.
