BIOL 2051 Chapter : Ch 15 And 16
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At this point, pyruvate can either be used: in fermentation to form fermentation products (alcohols, acids, gases) in respiration (tca cycle) to be fully oxidized to carbon dioxide. Fermentation vs. respiration: fermentation from 1 glucose molecule a net of 2 atp are produced. Partial oxidation of glucose reduction of pyruvate fermentation products: nad, respiration from 1 glucose molecule up to 38 atp are produced. Oxidation of pyruvate by citric acid cycle. Fermentation: during fermentation, glycolysis occurs followed by fermentation reactions. (no tca, no etc, during glycolysis, electrons from glucose are passed to 2 nad+ creating 2 nadh. In fermentation, electrons from nadh are passed to pyruvate, regenerating nad+ so glycolysis can continue. In this process (glycolysis followed by fermentation reactions), net gain of 2 atp are made by substrate level phosphorylation: fig. 13. 21 start with pyruvic acid from glycolysis >> converted to>> alcohol, lactic acid, propionic acid (swiss cheese), isopropanol: **nadh is converted back to nad in all those conversions.
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Fill in the blank in the following table:
metabolic cycle | location pro/ eukaryote | components | substrates | products | pathway purpose |
embden- meyerhof- parnas (glycolysis) | cytoplasm/ cytoplasm | 10 enzymes | |||
pentose phosphate pathway | cytoplasm/ cytoplasm | dozen enzyme | 1 Glucose (6 carbon), 1 NADP, 1ATP | 1 Ribose-P (5 carbon) + 1CO2, 1NADPH, or sugars, 1 ADP | Nucleotide synthesis, NADPH for anabolism |
PDH reaction | cytoplasm/ mitochondria matrix | ||||
TCA/ Krebs/ citric acid cycle | generation of high energy electron carriers, provide metabolic precursors | ||||
Electron transport chain + ATP synthase (aerobic respiration) | |||||
Electron transport chain + ATP synthase (anaerobic respiration) | 1Nitrate or sulfate or CO2, 1NADH + ____ ADP Or 1FADH2+ ____ ADP | N2, or NO2 or H2S or CH4 1NAD + ____ ATP Or 1FADH2+ ____ ATP | Generate proton motive forces abd use to generate ATP regenerate NAD+ | ||
Fermentation | cytoplasm/ cytoplasm | 1 or more enzymes (vary by organism) | 1 pyruvate, 1 NADH | 1 alcohol or acid (maybe 1 CO2) NAD+ | Regenerate NAD+ |