NURS 3331 Chapter Notes - Chapter 74: Hyperglycemia, Hyperuricemia, Indometacin
Document Summary
Uric acid level greater than 7 mg/dl in men or greater than 6 mg/dl in women. Episodes of severe joint pain (typically in large toe) Long-term to lower blood levels of uric acid. Relief should be within 24 hours; swelling subsides over next few days. Gi ulceration decreased renal function fluid retention increased risk of cardiovascular events. Indomethacin (indocin) severe frontal headache is common adverse effect (30- 50%) Diclofenac (voltaren) abd pain, dyspepsia, nausea common adverse effects. Useful for patients who are hypersensitive to, are unresponsive to, or have medical conditions that contraindicate the use of nsaids. Now reserved for patients who are unresponsive/intolerant to safer agents. Indicates injury to the cells of the gi epithelium and should be stopped immediately regardless of status of joint pain. Because these drugs have no analgesic or anti-inflammatory actions, they are not useful in an acute gouty attack.
