BIO 2306 Chapter Notes - Chapter 8: Chromosome Abnormality, Microscope Slide, Haploinsufficiency

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Metacentric : centromere is located approximately in the middle, has two arms of equal length. Submetacentric : centromere is displaced toward one end, creates a long arm ( q ) and a short arm ( p ) Acrocentric : centromere near one end, produced a long arm and a knob (satellite) at the other end. Telocentric : centromere at or very near the end of the chromosome. Chromosome rearrangements : alter the structure of chromosomes, can be duplicated, deleted, or inverted. Aneuploidy : the number of chromosomes is altered, one of more individual chromosomes are added or deleted. Polyploidy : one or more complete sets of chromosomes is added, any organism that has more than two sets of chromosomes (i. e. 3n, 4n) Chromosome rearrangements : chromosome mutations that change the structures of individual chromosomes, 4 basic types. Duplications : part of the chromosome has been doubled, ab-cdefg ab-cdefefg.

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