SOCI 3630 Chapter Notes - Chapter 4.4: Torsades De Pointes, Sinus Rhythm, Ventricular Fibrillation
4 Jun 2020
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Can be used to convert someone from a fib to sinus rhythm and for maintenance of sinus rhythm as well. Conversion is a one-time dose, maintenance isn"t. Dizziness, visual disturbances, palpitations, dyspnea, chest pain, tachycardia, headaches (cns stuff) Proarrhythmic effect in people with mi or decreased ef. Different from fleicanide due to metabolism with 3a4. Tid dosing, extended release is not available in canada. Avoid in renal insufficiency and females >65 particularly on a diuretic (high risk of torsades de pointes) This is a beta blocker with a risk of torsades (5%) if not used properly. Hypokalemia is a risk factor for torsades. What agents can we use to convert someone to sinus rhythm from a fib: Fleicanide and propafenone: one time dose for conversion. Effective 80-90% of time, but to cardiovert the patient has to be sedated (if not possible then use drugs instead or addition to these drugs)
